We caught the stars of Grey’s Anatomy on the red carpet and grilled them for details on the show’s highly anticipated 15th season!

Grey’s Anatomy – Season 15

As the long-running ABC medical drama returns for an unbelievable 15th season, Camilla Luddington gave us a preview of what’s happening in the premiere episode.

The season picks up with Jo and Alex on their honeymoon, during which Jo gets hit with inspiration for a new medical innovation. She also concludes that Meredith may be the right person to pursue it with.

Off-screen, Luddington talks about the excitement of reconnecting with Grey’s fans, still passionate after a decade and a half.

Kelly McCreary explained what it’s like to work with such a talented, ensemble cast, how they interact behind the scenes, and what they learn from each other.

Grey’s Anatomy returns to ABC on September 27th.